Dr. Dai-Min Zhang earned his M.D. in 1994 and went on to earn his Ph.D. in Biophysics and cardiac physiology from Suzhou University. He completed post-doctoral training at Mayo Clinic (in Cardiovascular Diseases) and at UC Davis (in Cardiology, Physiology and Membrane Biology).
Dr. Dai-Min Zhang research is to understand the functional regulation of ion channels in the cardiovascular system. Currently, he is an interventional Cardiology physician in the Department of Cardiology of Nanjing First Hospital, affiliated to Nanjing Medical University, China.
- 1989-1994: Medical Science- Wannan Medical College, China.
- 2000-2003: Cardiac Electrophysiology- Kunming Medical College, China.
- 2005-2008: Physiology and Biophysics- Suzhou University, China.
- 2008-2010: Cardiovascular Diseases- Mayo Clinic, Rochester, USA.
- 2010-2014: Physiology and Biophysics- University of California at Davis, USA.
- Daimin Zhang, MinghuaHan, Tao Guo. Advancing of treating congestive heart failure with angiotensin-II receptor antagonists. South China Journal of Cardiovascular Diseases, 2001, 7(14): 287-288.
- Daimin Zhang, Tao Guo, ShuminLi. Development and evaluation of quality of life instrument for patients with pacemaker.Chinese Journal of Clinical Rehabilitation,2002,6(23):3490-3491.
- Daimin Zhang, Tao Guo.Effect of pacemaker parameter on quality of life in patients.South China Journal of Cardiovascular Diseases,2003,9(2):142-145.
- Daimin Zhang, ZhigangYu,YucaiXie.Progress in cardiac pacing applications. Shanghai Medicine Journal,2005, 28(S): 220-222.
- Daimin Zhang, Ming Luo. Progress on sleep apnea syndrome and cardiopulmonary disease. Shanghai Medicine Journal, 2005, 28(S):200-201.
- Daimin Zhang, Ming Luo.Progress in diagnosis and treatment of pulmonary artery embolism.Shanghai Medicine Journal, 2005, 28(S):214-216.
- Daimin Zhang, ZhihaLiu, Tao Guo, ShuminLi, XiangjunYang, JianpingSong, TingboJiang, Wenping Jiang. Evaluation of Reliability and Validity of SF-36 Health Survey in Patients with Pacemaker. Suzhou University Journal of Medical Science, 2007, 27(5):777-779.
- Daimin Zhang, ZhihuaLiu. Simvastatin prevents Angiotensin II induced the changes of T type calcium current in cultured neonatal rat heart cell. Clinical Cardiology, 2007, 30(S): 189-190.
- Daimin Zhang,ZhihuaLiu,Tao Guo, ShuminLi,XiangjunYang,JiangpingSong,WenpingJiang. Assessment of quality of life in patients with pacemaker by Health survey questionnaire. Chinese Journal of Behavioral Medical Science,2007,16(11):1046.
- Daimin Zhang, ZhihuaLiu. Pleiotropic effects of the statins on cardiovascular diseases. International Journal Cardiovascular Diseases, 2008, 35(1):42-45.
- Daimin Zhang,ZhihuaLiu.Advance of T type calcium current on cardiomyocytes.Chinese Journal of Cardiovascular Medicine,2008, 13(1):63-65.
- Daimin Zhang, ZhihuaLiu. Advance of the Statins on Ion Channels. China Medicine,2008,3(3):160-161.
- YangzhenShao,DaiminZhang,XunLi,WenpingJiang.The molecular mechanism of transient outward potassium currents decreasing in ventricles from diabetic rats.Chinese Journal of Cardiac Electrophysiology and Pacing,2008,23(3):189-195.
- YangzhenShao, Daimin Zhang, XunLi, WenpingJiang. The alterations of transient outward potassium currents in ventricular myocytes from diabetic rats. Chinese Journal of hypertension.2008,16(6):512-514.
- Daimin Zhang, Zhihua Liu, Tao Guo, ShuminLi, JianpingSong, TingboJiang, XiangjunYang, WenpingJiang. Quality of life for patients with pacemaker by dynamic modified pacing system.Jiangsu Medical Journal,2008,34(4):325-327.
- Yangzhen Shao, Daimin Zhang, Xun Li, WenpingJiang. Isolation of ventricular myocytes of adult diabetic rats.Chinese Heart Journal,2009,21(2): 209-210.
- Dai-Min Zhang, Tongrong He, Zvonimir S. Katusic, Hon-Chi Lee, Tong Lu. Muscle-Specific F-Box Only Proteins Facilitate BK Channel ß1 Subunit Downregulation in Vascular Smooth Muscle Cells of Diabetes Mellitus. Circulation Research. 2010;107(12):1454-1459.
- Tong Lu, Dai-Min Zhang, Xiao-Li Wang, Tongrong He, Ru-Xing Wang, Qiang Chai, Zvonimir S. Katusic, Hon-Chi Lee. Regulation of Coronary Arterial BK Channels by Caveolae-Mediated Angiotensin II Signaling in Diabetes Mellitus.Circulation Research. 2010; 106(6):1164-73.
- Yongping Chai, Dai-Min Zhang, Yu-Fung Lin. Activation of cGMP-dependent protein kinase stimulates cardiac ATP-sensitive potassium channels via a ROS/calmodulin/CaMKII signaling cascade. PLoS ONE 2011, 6(3): e18191.
- Xiao-Dong Zhang, ValeriyTimofeyev, Ning Li, Richard E. Myers, Dai-Min Zhang, Anil Singapuri, Victor C. Lau, Chris T. Bond, John Adelman, Deborah K. Lieu, NipavanChiamvimonvat.Critical roles of a small conductance Ca2+-activated K + channel (SK3) in the repolarization process of atrial myocytes. Cardiovascular Research. 2014, 101(2):317-325doi:10.1093/cvr/cvt262. Epub 2013 Nov 26.
- Dai-Min Zhang, Yongping Chai, Jeffrey R. Erickson, Joan Heller Brown, Donald M. Bers, Yu-Fung Lin. Intracellular signaling mechanism responsible for modulation of sarcolemmal ATP-sensitive potassium channels by nitric oxide in ventricular cardiomyocytes. J. Physiol.(London). 2014, 592(5): 971-990.
- Wen Wu, Daimin Zhang, Daorong Pan, GuangfengZuo, Xiaomin Ren, Shaoliang Chen. Downregulation of vascular endothelial growth factor receptor-2 under oxidative stress conditions is mediated by ß-transduction repeat-containing protein via glycogen synthase kinase-3 ß signaling. International journal of molecular medicine, 2016, 37(4):911-920.
- Xu Tang, Ling-Ling Qian, Ru-Xing Wang, Yong Yao, Shi-Peng Dang, Ying Wu, Wen Wang, Yuan Ji, Man-Qing Sun, Da-Yun Xia, Xiao-Yu Liu, Dai-Min Zhang, Qiang Chai, Tong Lu.Regulation of Coronary Arterial Large Conductance Ca2+-Activated K+ Channel Protein Expression and Function by n-3 Polyunsaturated Fatty Acids in Diabetic Rats.J Vasc Res 2017;54(6):329–343.
- Mingxia Gu, Yanrong Zhu, Xiaorong Yin, Dai-Min Zhang.Small Conductance Ca2+-Activated K+ Channels:Insights into Their Roles in Cardiovascular Diseases. Experimental & Molecular Medicine, 2018,13;50(4):23.
- Yanrong Zhu, Peng Ye, Shao-liang Chen, Dai-Min Zhang. Functional Regulation of Large Conductance Ca2+-activated K+ Channels in Vascular Diseases. Metabolism, Clinical and Experimental, 2018;83:75-80.
- Yanrong Zhu, Xiao-Xin Jiang, Yaguo Zheng, Jing Xiong, Dongping Wei, Dai-Min Zhang. Modulation of Cardiomyocytes Depends on A-kinase Anchoring Protein Complex Signaling Cascades.Journal of cellular and molecular medicine. 2019Sep 11.
- Peng Ye, Yue Gu, Yanrong Zhu, Dai-Min Zhang, Shao-liang Chen. Functional Protection against Cardiac diseases depends on ATP-sensitive potassium channels. J Cell Mol Med. 2018;22(12):5801-5806.
- Yan-Rong Zhu, Xiao-Xin Jiang, Dai-Min Zhang. Critical regulation of atherosclerosis by the KCa3.1 channel and the retargeting of this therapeutic target in in-stent neoatherosclerosis. Journal of Molecular Medicine.2019 Jun 28.
- Dai-Min Zhang, Hong-Ming Liu, Shaoliang Chen. In-stent restenosis and drug coated balloon: insight from clinical therapeutic strategy.
- Ling-Ling Qian, Man-qing Sun, Ru-Xing Wang, Tong Lu, Ying Wu, Shi-peng Dang, Xu Tang, Yuan Ji, Xiao-yu Liu, Xiao-xi Zhao, Wen Wang, Qiang Chai, Dai-min Zhang, Hon-Chi Lee. Mechanisms of BK Channel Activation by Docosahexaenoic Acid in Rat Coronary Arterial Smooth Muscle Cells.Frontiers in Pharmacology.2018;9:223.
- Peng Ye, Yue Gu, Yan-Rong Zhu, Yue-Lin Chao, Xiang-Quan Kong, Jie Luo, Xiao-Min Ren, Guang-Feng Zuo, Dai-Min Zhang, Shao-Liang Chen. Exogenous hydrogen sulfide attenuates the development of diabetic cardiomyopathy via the FoxO1 pathway. J Cell Physiol. 2018;233(12):9786-9798.
- Yan-Rong Zhu, Xiao-Xin Jiang, Peng Ye, Shao-liang Chen,Dai-Min Zhang. Potassium Channels in the Vascular Diseases.Vascular Biology, 2019, intechopen.comdoi: 10.5772/intechopen.82474.
- Yan-Rong Zhu, Xiao-Xin Jiang, Peng Ye, Guang-Feng Zuo, Zhi-Mei Wang, Lin-Lin Zhu, Yaguo Zhen, Zhizhong Liu, Shao-Liang Chen,Dai-Min Zhang. Knockout of AKAP150 Improves Impaired BK Channel-Mediated Vascular Dysfunction through the Akt/GSK3ß Signaling Pathway in Diabetes Mellitus.
- Xiao-Xin Jiang, Yan-Rong Zhu, Hong-Ming Liu, Shao-Liang Chen, Dai-Min Zhang. Effect of BIN1 on cardiac dysfunction and malignant arrhythmia.
- Mingxia Gu, Xiao-Xin Jiang, Yingqiang Zhang, Yan-Rong Zhu, Jing Wang, Qianru Chen, Sidonio Augusto Mesquita Viana, Shaoliang Chen, Xiaorong Yin, Dai-Min Zhang. Improving the efficacy of warfarin in elderly patients with atrial fibrillation with the assistance of a family mobile app.
- Tang CX, Wang YN, Zhou F, Schoepf UJ, Assen MV, Stroud RE, Li JH, Zhang XL, Lu MJ, Zhou CS, Zhang DM, Yi Y, Yan J, Lu GM, Xu L, Zhang LJ. Diagnostic performance of fractional flow reserve derived from coronary CT angiography for detection of lesion-specific ischemia: A multi-center study and meta-analysis. Eur J Radiol. 2019 Jul;116:90-97.
- Dai-Min Zhang, Xuan Sun, Xiao-Xin jiang, Yan-Rong Zhu, Peng Ye, Linlin Zhu, Yangzhen Shao, Xiaobo Li, Zhizhong Liu, Yaguo Zhen, Shaoliang Chen. The efficacy and safety of Dabigatran combined with Aspirin in elderly patients with nonvalvular atrial fibrillation.
- Tang CX, Liu CY, Lu MJ, Schoepf UJ, Tesche C, Bayer RR 2nd, Hudson HT Jr, Zhang XL, Li JH, Wang YN, Zhou CS, Zhang JY, Yu MM, Hou Y, Zheng MW, Zhang B, Zhang DM, Yi Y, Ren Y, Li CW, Zhao X, Lu GM, Hu XH, Xu L, Zhang LJ.CT FFR for Ischemia-Specific CAD With a New Computational Fluid Dynamics Algorithm: A Chinese Multicenter Study.JACC Cardiovasc Imaging. 2019 Aug 14. pii: S1936-878X(19)30605-9.
- Excellent Graduate Student Scholarship Award for Master Degree, Conferred in 2001, Kunming Medical College, P. R. China.
- Outstanding Graduate Student Award for Master Degree, Conferred in 2002, Kunming Medical College, P. R. China.
- Science and Technology Advancement Prize (3rd place), Conferred in 2006, Science and Technology Association of Yunnan Province, P. R. China.
- Excellent Graduate Student Scholarship Award for Philosophy Degree, Conferred in 2007, Suzhou University, P. R. China.
- Fund Program for the Scientific Activities of Selected Returned Overseas Professionals in Nanjing, Conferred in 2014, Nanjing, Jiangsu, P. R. of China.
- High level innovation and entrepreneurship talent introduction plan in Jiangsu province, Conferred in 2015, Jiangsu, P. R. of China.
- Distinguished Medical Expert in Jiangsu Province, Conferred in 2015, Jiangsu Province, P. R. China.
- Outstanding contribution to Nanjing middle-aged and young experts, Conferred in 2015, Nanjing, Jiangsu Province, P. R. of China.
- 333 talents project in Jiangsu Province, Conferred in 2016, Jiangsu Province, P. R. of China.
- Six talent peaks project in Jiangsu Province, Conferred in 2016, Jiangsu Province, P. R. China.
