Successful Desensitization of Trikafta after Hypersensitivity Rash
Hypersensitivity rashes caused by Cystic Fibrosis Transmembrane Regulator (CFTR) modulators are rare, and there is no standard protocol on how to reinitiate the drug after the reaction. A 47-year-old woman with Cystic Fibrosis (CF) developed a maculopapular rash with Elexacaftor/Tezacaftor/Ivacaftor (ELX/TEZ/IVA). Since ELX/TEZ/IVA therapy produced a significant clinical response in the patient, and there is no other therapy that is as effective, we decided to use a slow desensitization protoco...
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