Xiaowei Yu, Male, PhD, chief physician, PhD supervisor of Shanghai Jiaotong University & Shanghai Ocean University, is currently the director of orthopaedics, Shanghai Sixth People's Hospital East Campus.
Xiaowei Yu was selected in 2018 as the Shanghai Excellent Academic Leadership Program. I have headed three projects of the National Natural Science Foundation of China.
Xiaowei Yu has published more than 30 SCI as first or correspondent Author.
- Jiang C, Xia W, Wu T, Pan C, Shan H, Wang F, et al. Inhibition of microRNA-222 up-regulates TIMP3 to promotes osteogenic differentiation of MSCs from fracture rats with type 2 diabetes mellitus. J Cell Mol Med. 2019 Nov 6. doi: 10.1111/jcmm.14777.
- Jiang F, Yin F, Lin Y, Xia W, Zhou L, Pan C, et al. The promotion of bone regeneration through CS/GP-CTH/antagomir-133a/b sustained release system. Nanomedicine. 2019;24:102116. doi: 10.1016/j.nano.2019.102116.
- Jiang F, Shan H, Pan C, Zhou Z, Cui K, Chen Y, et al. ATP6V1H facilitates osteogenic differentiation in MC3T3-E1 cells via Akt/GSK3ß signaling pathway. Organogenesis. 2019;15(2):43-54.
- Zhou Z, Pan C, Wang N, Zhou L, Shan H, Gao Y, et al. A high-fat diet aggravates osteonecrosis through a macrophage-derived IL-6 pathway. Int Immunol. 2019;31(4):263-273.
- Pan C, Shan H, Wu T , Liu W, Lin Y, Xia W, et al. 20(S)-Protopanaxadiol Inhibits Titanium Particle-Induced Inflammatory Osteolysis and RANKL-Mediated Osteoclastogenesis via MAPK and NF-?B Signaling Pathways. Front Pharmacol. 2019;9:1538.
- Zhou Z, Seta J, Markel DC, Song W, Yurgelevic SM, Yu XW*, et al. Release of vancomycin and tobramycin from polymethylmethacrylate cements impregnated with calcium polyphosphate hydrogel. J Biomed Mater Res B Appl Biomater. 2018;106(8):2827-2840.
- Pan C, Zhou Z, Yu X*. Coatings as the useful drug delivery system for the prevention of implant-related infections. J Orthop Surg Res. 2018;13(1):220. Review.
- Zhou Z, Pan C, Lu Y, Gao Y, Liu W, Yin P, et al. Combination of Erythromycin and Curcumin Alleviates Staphylococcus aureus Induced Osteomyelitis in Rats. Front Cell Infect Microbiol. 2017;7:379.
- Wang N, Wang F, Gao Y, Zhou Z, Liu W, Pan C, et al. Solanum Muricatum Promotes Osteogenic Differentiation of Rat Bone Marrow Stromal Cells. J Food Sci. 2017;82(7):1775-1780. [Epub ahead of print].
- Chen F, Ni Y, Liu B, Zhou T, Yu C, Su Y, et al. Self-crosslinking and injectable hyaluronic acid/RGD-functionalized pectin hydrogel for cartilage tissue engineering. Carbohydr Polym. 2017;166:31-44.
- Zhou W, Yuan T, Gao Y, Yin P, Liu W, Pan C, et al. IL-1ß-induces NF-?B and upregulates microRNA-372 to inhibit spinal cord injury recovery. J Neurophysiol. 2017;117(6):2282-2291.
- Wang F, Wang N, Gao Y, Zhou Z, Liu W, Pan C, et al. ß-Carotene suppresses osteoclastogenesis and bone resorption by suppressing NF-?B signaling pathway. Life Sci. 2017 Mar 3;174:15-20. [Epub ahead of print].
- Wang F, Guan X, Wu T, Qiao J, Han Z, Wu J, et al. Acellular Endocardium as a Novel Biomaterial for the Intima of Tissue-Engineered Small-Caliber Vascular Grafts. Artif Organs. 2016;40(12):E253-E265.
- Wang N, Zhou Z, Wu T, Liu W, Yin P, Pan C, et al. TNF-a-induced NF-?B activation upregulates microRNA-150-3p and inhibits osteogenesis of mesenchymal stem cells by targeting ß-catenin. Open Biol. 2016 Mar;6(3). pii: 150258. doi: 10.1098/rsob.150258.
- Chen C, Lu J, Yu Q, Xiao JR, Wei HF, Song XJ, et al. Expression of CDc6 after acute spinal cord injury in adult rats. Neuropeptides. 2016;56:59-67.
- Zhao J, Chen C, Xiao JR, Wei HF, Zhou XH, Mao XX, et al. An Up-regulation of IRF-1 After a Spinal Cord Injury: Implications for Neuronal Apoptosis. J Mol Neurosci. 2015;57(4):595-604.
- Chen F, Yu S, Liu B, Ni Y, Yu C, Su Y, et al. An Injectable Enzymatically Crosslinked Carboxymethylated Pullulan/Chondroitin Sulfate Hydrogel for Cartilage Tissue Engineering. Sci Rep. 2016;6:20014.
- Feng W, Gang L, Xin G, Han ZQ, Yu XW*Yu XW*, You QJ*. Overexpression of eNOS decrease tissue factor (TF) level in CD34+ cells exhibit increased antithrombogenic property in small caliber vascular graft. J Cardiovasc Surg (Torino). 2015 Sep 3. [Epub ahead of print]
- Yu XWYu XW, Wu TY, Yi X, Ren WP, Zhou ZB, Sun YQ, et al. Prognostic significance of VEGF expression in osteosarcoma: a meta-analysis. Tumour Biol. 2014;35(1):155-60.
- Yu XWYu XW, Ai ZS, Gao YS, Zhang CQ*. Blood loss closely correlates with body mass index in total hip arthroplasty performed through direct lateral approach. Saudi Med J. 2013;34(7):709-13.
- Song W, Yu X*Yu X*, Markel DC, Shi T, Ren W*. Coaxial PCL/PVA electrospun nanofibers: osseointegration enhancer and controlled drug release device. Biofabrication. 2013;5(3):035006.
- Wu T, Zhang Q, Ren W, Yi X, Zhou Z, Peng X, et al. Controlled release of gentamicin from gelatin/genipin reinforced beta-tricalcium phosphate scaffold for the treatment of osteomyelitis. J Mater Chem B. 2013;(26),3304-3313.
- Yu XYu X, Tang M, Zhou Z, Peng X, Wu T, Sun Y*. Minimally invasive treatment for pubic ramus fracture combined with sacroiliac joint complex injury . Int Orthop. 2013;37(8):1547-54.
- Yu XYu X, Jiang W, Pan Q, Wu T, Zhang Y, Zhou Z, et al. Umbrella-shaped, memory alloy femoral head support device for treatment of avascular osteonecrosis of the femoral head. Int Orthop. 2013;37(7):1225-32.
- Wu TY, Zhou ZB, He ZW, Ren WP, Yu XW*Yu XW*, Huang Y*. Reinforcement of a new calcium phosphate cement with RGD-chitosan-fiber. J Biomed Mater Res A. 2014;102(1):68-75.
- Yu XYu X Zhao X, Wu T, Zhou Z, Gao Y, Wang X, Zhang CQ*. Inhibiting wear particles-induced osteolysis with naringin. Int Orthop. 2013;37(1):137-43.
- Yu XYu X, Zhong Y, Zhu Z, Wu T, Shen A*, Huang Y*. Increased expression of nitric oxide synthase interacting protein (NOSIP) following traumatic spinal cord injury in rats. J Mol Histol. 2012;43(6):661-8.
- Yu XYu X, Wen H, Cao J, Sun B, Ding T, Li M, et al. Temporal and Spatial Expression of KIF3B after Acute Spinal Cord Injury in Adult Rats. J Mol Neurosci. 2013;49(2):387-94.
- Zhong Y, Huang Y, Cao J, Lu X, Feng M, Shen G, et al. Increase in phosphorylation of PDK1 and cell survival after acute spinal cord injury. J Neurol Sci. 2012;320(1-2):38-44.
- Wu T, Hua X, He Z, Wang X, Yu X*Yu X*, Ren WP. The bactericidal and biocompatible characteristics of reinforced calcium phosphate cements. Biomed Mater. 2012;7(4):045003.
- Yu XWYu XW, Xie XH, Yu ZF, Tang TT. Augmentation of Screw Fixation with Injectable Calcium Sulfate Bone Cement in Ovariectomized Rats. J Biomed Mater Res B Appl Biomater. 2009;89(1):36-44.
- Xie XH, Yu XWYu XW, Zeng SX, Du RL, Hu YH, Yuan Z, et al. Enhanced osteointegration of orthopaedic implant gradient coating composed of bioactive glass and nanohydroxyapatite. J Mater Sci Mater Med. 2010;21(7):2165-73.
HONORS/AWARDS/RECOGNITION:
- 2009: Outstanding Teacher Award, the Second Clinical Medical College of Nanjing Medicaluniversity, Jiangsu, China.
- 2011: Medical Talents of Jiangsu Province, Jiangsu, China, 2011.
- 2012: High Level Talents of Six Major Industries of Jiangsu Province , Jiangsu, China.
PATENTS:
- A novel stirred syringe for adding the biologically active factor or drug (No. ZL 201120343315.8, Utility model patents of China).
- A novel dynamic hip screw for augmentation with injectable bone cement (No. ZL 2009 2 0209687.4, Utility model patents of China).
- A type of internal fixator for pelvis (No. ZL 201120150481.6, Utility model patents of China).
- A type of internal fixator for limb fracture (No. ZL 201120303770.5, Utility model patents of China).
- Application of a novel internal fixator for pelvis (No. ZL201110122458.0; Invention patent of China).
- A type of internal fixator for limb fracture (No.: 201110239369.4; Utility model patents of China).
- An internal fixation device for acetabular posterior wall fracture (No.: 20132 0018250.9; Utility model patents of China).
- A device for limb local administration and dialysis (No.: 2014 2 0660309.9; Utility model patents of China).
- An internal fixation device for acetabular posterior wall fracture (No.: 2013 1 0013348.X; Invention patent of China).
- A proximal fixation prosthesis of hip joint (No.: 2015 2 0004498.9; Invention patent of China).
- An appearance design of proximal coating prosthesis(No.: 2015 3 0004127.6; Invention patent of China).
- An appearance design of distal coating prosthesis (No.: 2015 3 0004265.4; Invention patent of China).
- Fingerstall-cannulated guide for fast and accurate guide wire positioning (Application No.: 14/092,987; Invention patent of US).
- A novel stirred syringe for adding the biologically active factor or drug (application No. :201110270975.2; Invention patent of China).
- Device and method for electrospinning multiple layered and three dimensional nanofibrous composite materials for tissue engineering (application Ser No. 14/098,711; Invention patent of US).
- A device for limb local administration and dialysis (Application No.: 201410621027.2; Invention patent of China).
