- BENSAMOUN Sabine Fanny, received a PhD in Biomechanics at the University of Technology of Compiègne (UTC) in 2003. Then, she moved to the Mayo Clinic (Rochester, MN) to join the Orthopaedic Biomechanics laboratory as a research fellow. Two years later, she got a full time research position in the Biomechanics department of UTC. In 2019.
- BENSAMOUN Sabine Fanny, becomes CNRS research director and she is a research collaborator at the Mayo Clinic. Her h-index is 19 and she has obtained several prizes (Biomechanics Society, Coverage for Bone Journal, Young Investigator « silver » 6th world congress of Biomechanics, …). Her scientific approach is to associate the fundamental and the clinical research. To achieve her research, she built many national and international partnerships and she obtained private and public subventions.
- BENSAMOUN Sabine Fanny, training performed at the Mayo Clinic allowed her to apply her fundamental knowledge by conducting a study called Magnetic Resonance Elastography. She realizes different clinical studies applied to fibrotic liver and muscle myopathy. In addition, she develops ultrasound elastography to analyze thin muscle implicated in the facial expression, or located in the hindlimb of mice, to evaluate the treatment. In parallel, she leads a multidisciplinary muscle study through a multi scale analysis to determine the role of the TIEG gene on the skeletal muscle.
ARTICLES:
- Bensamoun S., Ho Ba Tho M.C., Luu S., Gherbezza J.M., De Belleval J.F. 2004 Spatial distribution of acoustic and elastic properties of human femoral cortical bone. J of biomechanics. 37:503-510.
- Bensamoun S., Gherbezza J.M., De Belleval J.F., Ho Ba Tho M.C. 2004. Transmission scanning acoustic imaging of human cortical bone and relation with the microstructure. Clin Biomech. 19:639-647.
- Bensamoun S., Ringleb S., Chen Q., Ehman R., An K.N. 2005. Mechanical Properties of Relaxed and Contracted Thigh Muscles using Magnetic Resonance Elastography. Comput Methods Biomech Biomed Engin. Sep;Supp 1:31-2.
- Ho Ba Tho M.C., Bensamoun S., Vanleene M, Treutenaere J.M., Rey C 2005. Caractérisation et modélisation multi-échelle du tissu osseux. La fragilité osseuse et ses déterminants-Appareil Locomoteur, p 9-12.
- Bensamoun S.F., Ringleb S.I., Littrell L., Chen Q., Brennan M., Ehman R.L., An K.N. 2006. Determination of thigh muscle stiffness using magnetic resonance elastography. J Magn Reson Imaging. 22:242-247.
- Bensamoun S., Stevens L., Fleury M.J, Bellon G., Goubel F., Ho Ba Tho M.C. 2006. Macroscopic-microscopic characterization of the passive mechanical properties in rat soleus muscle. J of Biomech. 39(6):568-578.
- Bensamoun S.F., Subramaniam M., Hawse J.R., Ilharreborde B., Bassillais A., Benhamou C.L., Fraser D.G., Oursler M.J., Amadio P.C., An K.N., Spelsberg T.C. 2006. TGF-Beta Inducible Early Gene-1 Knockout Mice Display Defects in Bone Strength and Microarchitecture. Bone. 39:1244-1251.
- Bensamoun S.F., Tsubone T., Subramaniam M., Hawse J.R., Boumediene E., Spelsberg T.C., inducible early?An K.N., Amadio P.C. 2006 Age-dependent changes in the mechanical properties of tail tendons in TGF gene-1 (TIEG) knockout mice. J Appl Physiol. 101(5):1419-1424.
- Basillais A., Bensamoun S., Chappard C., Brunet-Imbault B., Lemineur G., Ilharreborde B., Ho Ba Tho M.C., Benhamou C.L. 2007. Three dimensional characterization of cortical bone microstructure by micro-computed tomography : validation with ultrasound and microscopic measurements. J Orthop Science. 12(2):141-148.
- Bensamoun S.F., Ringleb S., Chen Q., Ehman R.L., An K.N., Brennan M. 2007. Thigh muscle stiffness assessed with magnetic resonance elastography in hyperthyroid patients before and after medical treatment. J Magn Reson Imaging. 26(3):708-713.
- Chen Q., Bensamoun S.F., Basford J.R., Thompson J.M., An K.N. 2007. Identification and quantification of myofascial taut bands with magnetic resonance elastography. Arch Phys Med Rehabil. 88(12):1658-1661.
- Bensamoun S.F., Glaser K.J., Ringleb S.I., Chen Q., Ehman R.L., An K.N. 2008. Rapid magnetic resonance elastography of skeletal muscle using one dimensional projection. J Magn Reson Imaging. 27:1083–1088.
- Hawse J.R., Iwaniec U.T, Bensamoun S., Monroe D.G., Peters K.D., Rajamannan N.M., Oursler M.J., Turner R.T., Spelsberg T.C., Subramaniam M. 2008. TIEG-Null mice display a severe osteopenic gender-specific phenotype characterized by normal cancellous bone microarchitecture. Bone. 42:1025-1031. (Coverage for « Bone Journal ») .
- Bensamoun S.F., Wang L., Robert L., Charleux F., Latrive J.P., Ho Ba Tho M.C. 2008. Measurement of the liver stiffness with two imaging techniques: magnetic resonance elastography and fibroscan. J Magn Reson Imaging. 28:1287-1292.
- Bensamoun S.F., Fan Z., Ilharreborde B., Rho J.Y., Ho Ba Tho M.C. 2008. Assessment of mechanical properties of human osteon lamellae exhibiting various degrees of mineralization by nanoindentation. J Muscoskel Res. 11(3):1-9.
- Haddad O., Hawse J.R., Subramaniam M., Spelsberg T.C., Bensamoun S.F. 2009. TIEG1 osteocytes display defects in morphology, density and surrounding bone matrix. J Muscoskel Res. 12(3):127-136.
- Suwalski A., Dabboue H., Delalande A., Bensamoun S.F., Canon F., Midoux P., Saillant G., Klatzmann D., Salvetat J.P., Pichon C. 2010. Accelerated Achilles tendon healing by PDGF gene delivery with mesoporous silica nanoparticles. Biomaterials. 31(19):5237-5245.
- Gumez L., Bensamoun S.F., Doucet J., Haddad O., Hawse J.R., Subramaniam M., Spelsberg T.C., Pichon C. 2010. Molecular structure of tail tendon fiber in TIEG1 knockout mice structure using synchrotron diffraction technology. J Appl Physiol. 108:1706-1710.
- Bensamoun S.F., Robert L., Leclerc G., Debernard L., Charleux F., 2011. Stiffness imaging of the kidney and adjacent abdominal tissues measured simultaneously using magnetic resonance elastography (MRE). Clin Imaging. 35(4):284-287.
- Doucet J., Briki F., Gourrier A., Pichon C., Gumez L., Bensamoun S.F., Sadoc J.F. 2011. Modelling the lateral organization of collagen molecules in fibrils using the paracrystal Concept. J Struct Biol. 173(2):197-201.
- Debernard L., Robert L., Charleux F., Bensamoun S. 2011. Characterization of muscle architecture in children and adults using magnetic resonance elastography and ultrasound techniques. J Biomech. 44:397-401.
- Debernard L., Robert L., Charleux F., Bensamoun S. 2011. Analysis of thigh muscle stiffness from childhood to adulthood using Magnetic Resonance Elastography (MRE) technique. Clin Biomech. 26:836-840.
- Haddad O., Gumez L., Hawse J.R., Subramaniam M., Spelsberg T.C., Bensamoun S.F. 2011 TIEG1-null fibroblasts display age-dependent differences in their adhesion, spreading and proliferation. Exp Cell Res. 317:1726-1735.
- Leclerc G.E., Debernard L., Foucart F., Robert L., Pelletier K.M., Charleux F., Ehman R., Ho Ba Tho M.C., Bensamoun S.F. 2012. Characterization of a hyper-viscoelastic phantom mimicking biological soft tissue using an abdominal pneumatic driver with magnetic resonance elastography (MRE). J Biomech. 45:952-957.
- Debernard L., Robert L., Charleux F., Bensamoun S.F. 2013. A possible clinical tool to depict muscle elasticity mapping using magnetic resonance elastography (MRE). Muscle & Nerve. 47(6):903-908.
- Bensamoun S.F., Leclerc G.E., Debernard L., Cheng X., Robert L., Charleux F., Rhein C., Latrive J.P. 2013. Cutoff values for alcoholic liver fibrosis using magnetic resonance elastography technique. Alcohol Clin Exp Res. 37(5):811-817.
- Ho Ba Tho M.C., Mazeran P.E., El Kirat K., Bensamoun S.F. 2013. Multiscale Characterization of Human Cortical Bone. Comp Model Eng & Sciences. 87(6):557-577.
- Leclerc G.E., Charleux F., Robert L., Ho Ba Tho M.C., Rhein C., Latrive J.P., Bensamoun S.F. 2013. Analysis of the liver viscosity behavior as a function of the Multifrequency Magnetic Resonance Elastography (MMRE) post-processing. J Magn Reson Imaging. 38(2):422-428.
- Debernard L., Leclerc G.E., Robert L., Charleux F., Bensamoun S.F. 2013. In vivo characterization of the muscle viscoelasticity using mutifrequency MR elastography (MMRE). J Musculoskelet Res. 16(2):1350008-1-1350008-10.
- Bensamoun S.F., Dao T.T., Charleux F., Ho Ba Tho M.C. 2013. Estimation of in vivo muscle force derived from MR elastography: a preliminary study. J Musculoskelet Res. 16(3):1350015-1350025.
- Affagard J.S., Bensamoun S.F., Feissel P. 2014. Development of an inverse approach for the characterization of in vivo mechanical properties of the lower limb muscles. J Biomech Engin. 136:111012-1-111012-8.
- Leclerc G.E., Charleux F., Ho Ba Tho M.C., Bensamoun S.F. 2015. Identification process based on shear wave propagation within a phantom using finite element modelling (FEM) and magnetic resonance elastography (MRE). Comput Methods Biomech Biomed Engin (CMBBE). 18(5):485-491.
- Bensamoun S.F., Charleux F., Debernard L., Themar-Noel C., Voit T. 2015. Elastic properties of skeletal muscle and subcutaneous tissues in Duchenne muscular dystrophy by magnetic resonance elastography (MRE): a feasibility study. Innovation and Research in BioMedical engineering (IRBM). 36(1): 4-9.
- Affagard J.S., Feissel P., Bensamoun S.F. 2015. Measurement of the quadriceps muscles displacement and strain fields with ultrasound and Digital Image Correlation (DIC) techniques. Innovation and Research in BioMedical engineering (IRBM). 36(3):170-177.
- Chakouch M.K., Charleux F., Bensamoun S.F. 2015. New magnetic resonance elastography (MRE) protocol for quantifying elastic properties of nine thigh muscles. PlosOne. 10(9):e0138873. doi: 10.1371.
- Affagard J.S., Feissel P., Bensamoun S.F. 2015. Identification of hyperelastic properties of passive thigh muscle under compression with an inverse method from a displacement field measurement. Journal of Biomechanics. 48(15):4081-4086.
- Gennari J.M., Themar-Noel C., Panuel M., Bensamoun S., Deslandre C., Linglart A., Sokolowski M., Ferrari A. 2015. Adolescent spinal pain: The pediatric orthopedist's point of view. French Society of Spine Surgery (SFCR). Orthop Traumatol Surg Res. 101(6 Suppl):S247-250.
- Chakouch M.K., Pouletaut P., Charleux F., Bensamoun S.F. 2016. Viscoelastic shear properties of in vivo thigh muscles measured by magnetic resonance elastography. J Magn Reson Imaging. 43(6):1423-1433.
- Kammoun M., Même S., Même W., Subramaniam M., Hawse J.R., Canon F., Bensamoun S.F. 2016. Impact of TIEG1 on the structural properties of fast and slow twitch skeletal muscle. Muscle Nerve. 55(3):410-416.
- Kammoun M., Pouletaut P., Canon F., Subramaniam M., Hawse J.R., Vayssade M., Bensamoun S.F. 2016. Impact of TIEG1 deletion on the passive mechanical properties of fast and slow twitch skeletal muscles in female mice. PlosOne. Oct 13;11(10):e0164566. doi: 10.1371/journal.pone.0164566.s.
- Lamouille J., Müller C., Aubry S., Bensamoun S.F., Raffoul W., Durand S. 2017. Extensor indicis proprius tendinous transfer using shear wave elastography. Hand Surgery & Rehabilitation. Hand Surg Rehabil. 36(3):173-180.
- Ternifi R., Pouletaut P., Sasso M., Miette V., Charleux F., Bensamoun S.F.. 2018. Improvements of liver MR imaging clinical protocols to simultaneously quantify steatosis and iron overload. Innovation and Research in BioMedical engineering (IRBM). 39(3):219-225.
- Kammoun M, Ternifi R, Dupres V, Pouletaut P, Même S, Même W, Szeremeta F, Landoulsi J, Constans JM, Lafont F, Subramaniam M, Hawse JR, Bensamoun SF. 2019. Development of a novel multiphysical approach for the characterization of mechanical properties of musculotendinous tissues. Nature Scientific Reports. 9(1):7733. doi: 10.1038/s41598-019-44053-1.
- Kammoun M, Piquereau J, Nadal-Desbarats L, Même S, Beuvin M, Bonne G, Veksler V, Le Fur Y, Pouletaut P, Même W, Szeremeta F, Constans JM, Bruinsma ES, Nelson Holte MH, Najafova Z, Johnsen SA, Subramaniam M, Hawse JR, Bensamoun SF. 2019. Novel role of TIEG1 in muscle metabolism and mitochondrial oxidative capacities. Acta physiologica. doi: 10.1111/apha.13394.
- Ternifi R., Pouletaut P., Dakpé S., Testelin S., Devauchelle B., Charleux F., Constans J.M., Bensamoun S.F. 2019. First evaluation of zygomaticus major elastic properties using a US elastography technique. Journal of Biomedical Science and Engineering. 12(11):459-468.
- Ternifi R., Kammoun M., Pouletaut P., Subramaniam M., Hawse J.R., Bensamoun S.F. 2020. Ultrasound image processing to estimate the structural and functional properties of mouse skeletal muscle. Biomedical Signal Processing and Control. 56:101735
Electronic Posters presentation:
- Bensamoun S.F., Leclerc G, Charleux F, Rhein C, Latrive J.P. 2012. Magnetic resonance elastography (MRE): a non invasive technique to identify the cut-off values for alcoholic liver fibrosis. 47th European Association for the study of the liver (EASL), Barcelona, Spain.
- Debernard L, Robert L, Charleux F. Bensamoun S.F. 2012. MR elastography thigh muscle data base to detect age and gender related changes. 20th International Society for Magnetic Resonance in Medicine, Melbourne, Australia.
- Kammoun M., Hawse J.R., Subramaniam M., Bensamoun SF. 2016. Characterization of the passive mechanical properties of soleus fibers in TIEG1 mice. 22nd European Society of Biomechanics (ESB), Lyon, France.
