- Prof. Porro Chiara is an associate Professor of Human Anatomy at the Department of Clinical and Experimental Medicine - University of Foggia.
- She received PhD in “Applied Morphobiology and Cytometabolism of Drugs”, University of Bari. She was PhD host in the “Institute d’Hématologie et Immunologie Faculté de Médecine Université Louis Pasteur Strasbourg (France) and she was post doc host in the University of Angers (France) UMR CNRS 6214-INSERM 771.
- She has 35 publications and according to Scopus she has H index 15.
Her research interests are:
- Effects of microparticles harbouring Sonic Hedgehog on angiogenesis in vitro and in in vivo study;
- Isolation and characterization of microparticles from blood and sputum of cystic fibrosis and chronic obstructive pulmonary diseases patients and evaluation of microparticles effects in mice lung;
- Study of microparticles role in neurodegenerative diseases (Alzheimer e Parkinson);
- Study of resveratrol, curcumin, Folic Acid and Vitamin D and their anti-inflammatory action in modulatory response of microglia;
Education:
- 2001: Degree in Biological Sciences, University of Bari (Italy).
- 2001: Qualifying examination to practise.
- 2005: PhD in “Applied Morphobiology and Cytometabolism of Drugs”, University of Bari.
- 2005: Post PhD in the Department Human Anatomy, Faculty of Medicine, University of Bari.
- 2007-Present: Associate Professor of Human Anatomy, Department of Clinical and Experimental Medicine, Medical Faculty, University of Foggia (Italy).
Past Employment:
- 2001-2003: PhD student in the Department of Pharmacology and Human Physiology, Faculty of Medicine, University of Bari (Italy). Supervisors: Prof. D. Mitolo-Chieppa and Prof.V.Mitolo.
- 2003-2004: PhD host in the “Institute d’Hématologie et Immunologie Faculté de Médecine
- Université Louis Pasteur Strasbourg (France). Supervisors : Prof.J. M.Freyssinet and Prof. M.C. Martinez.
- 2005: Post-doc in the Department of Human Anatomy and Histology at the University of Bari Supervisors: Prof.V. Mitolo and Prof. M.A. Panaro.
- 2006-2007: Post doc host in the University of Angers (France) UMR CNRS 6214-INSERM 771, Supervisors: Prof. R. Andriantsitohaina and Prof. M.C. Martinez.
ACADEMIC APPOINTMENTS
Teaching activity:
- 2007- present: Assistant Professor of Human Anatomy in Medical School, Dentistry, Physical Education, Nursing Science at University of Foggia.
Member of Undergraduate and Master degree committees:
- Member of committees for the admission at the PhD school in “Applied Morphobiology and Cytometabolism of Drugs” .
- Member of committees for PhD degree in “Applied Morphobiology and Cytometabolism of Drugs” and “Sciences and cellular thechnologies”.
Institutional Activity:
- 2017-present: Coordinator of Faculty of Sport of the University of Foggia.
- 2013-present: Rector’s delegate for international student mobility.
- 2013-2016: Departimental coordinator for Erasmus plus program.
Institutional Affiliation:
- Department of Clinical and Experimental Medicine, University of Foggia - Medical Faculty - Az. Osp. OO.RR., Via Napoli 20, 71100 Foggia – Italy.
- Monda V, Carotenuto M, Precenzano F, Iacono D, Messina A, Salerno M, Sessa F, Lanzara V, Messina G, Quatrosi G, Nardello R, Operto FF, Santoro C, Moscatelli F, Porro C, Zammit C, Monda M, Pastorino GMG, Vetri L, Parisi L, Ruberto M, Roccella M. Neuropeptides' Hypothalamic Regulation of Sleep Control in Children Affected by Functional Non Retentive Fecal Incontinence. Brain Sci. 2020 Feb 25;10(3). pii: E129. doi: 10.3390/brainsci10030129.
- Antonia Cianciulli*, Chiara Porro*, Rosa Calvello, Teresa Trotta, ,Dario Domenico Lofrumento, Maria Antonietta Panaro. (2020). Microglia-mediated neuroinflammation: focus on PI3K modulation In revisione to: Biomolecules. 2020 Jan 14;10(1). pii: E137. doi: 10.3390/biom10010137. * These authors participated equally in this work. Q1, First author. I.F.:4,42
- Cianciulli Antonia*, Porro Chiara*, Lofrumento Dario Domenico, Trotta Teresa, Maria Antonietta Panaro. (2019). Curcumin regulates anti-inflammatory responses by JAK/STAT/SOCS signalling pathway in microglia. BIOLOGY. vol.;8(3). ISSN: 2079-7737, doi: 10.3390/biology8030051 * These authors participated equally in this work. Q1, First author.
- Porro C*, Panaro MA*, Lofrumento, DD, Hasalla E. Trotta T. (2019) The multiple roles of exosomes in Parkinson's Disease: an overview. IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY. vol. 41(4):469-476. doi: 10.1080/08923973.2019.1650371. *These authors participated equally in this work. Q3, First author.
- Teresa Trotta*, Maria A. Panaro*, Elona Prifti, Chiara Porro. (2019) Modulation of biological activities in glioblastoma mediated by Curcumin. NUTRITION AND CANCER. *These authors participated equally in this work . DOI: 10.1080/01635581.2019.1604978 Q2, Last and correspondig author.
- Porro, Chiara, Cianciulli, Antonia, Trotta, Teresa, Lofrumento, Dario Domenico, Calvello, Rosa, Panaro, Maria Antonietta (2019). Formyl-methionyl-leucyl-phenylalanine induces apoptosis in murine neurons: Evidence for no-dependent caspase-9 activation. BIOLOGY, vol. 8, ISSN: 2079-7737, doi: 10.3390/biology8010004 Q1, First author.
- Trotta T, Panaro M A, Cianciulli A, Mori G, Di Benedetto A, Porro C. (2018). Microglia-derived extracellular vesicles in Alzheimer's Disease: A double-edged sword. BIOCHEMICAL PHARMACOLOGY, ISSN: 0006-2952, doi: 10.1016/j.bcp.2017.12.020 Q1, Last and correspondig author..
- Di Benedetto, Adriana, Posa, Francesca, De Maria, Salvatore, Ravagnan, Giampietro, Ballini, Andrea, Porro, Chiara, Trotta, Teresa, Grano, Maria, Muzio, Lorenzo Lo, Mori, Giorgio (2018). Polydatin, Natural Precursor of Resveratrol, Promotes Osteogenic Differentiation of Mesenchymal Stem Cells. INTERNATIONAL JOURNAL OF MEDICAL SCIENCES, vol. 15, p. 944-952, ISSN: 14491907, doi: 10.7150/ijms.24111 Q1
- Posa, Francesca, Di Benedetto, Adriana, Cavalcanti-Adam, Elisabetta A., Colaianni, Graziana, Porro, Chiara, Trotta, Teresa, Brunetti, Giacomina, Lo Muzio, Lorenzo, Grano, Maria, Mori, Giorgio (2018). Vitamin D Promotes MSC Osteogenic Differentiation Stimulating Cell Adhesion and αVβ3 Expression. STEM CELLS INTERNATIONAL, vol. 2018, p. 1-9, ISSN: 1687-966X, doi: 10.1155/2018/6958713 Q2
- Cianciulli, Antonia, Porro, Chiara, Calvello, Rosa, Trotta, Teresa, Panaro, Maria Antonietta (2017). Resistance to apoptosis in Leishmania infantum-infected human macrophages: a critical role for anti-apoptotic Bcl-2 protein and cellular IAP1/2. CLINICAL AND EXPERIMENTAL MEDICINE, p. 1-11, ISSN: 1591-8890, doi: 10.1007/s10238-017-0482-1 Q2 Second author
- Cianciulli, Antonia*, Calvello, Rosa*, Porro, Chiara, Trotta, Teresa, Panaro, Maria Antonietta (2017). Understanding the role of SOCS signaling in neurodegenerative diseases: Current and emerging concepts. CYTOKINE & GROWTH FACTOR REVIEWS, vol. 37, p. 67-79-79, ISSN: 1359-6101, doi: 10.1016/j.cytogfr.2017.07.005 .*These authors participated equally in this work Q1. Second author
- Calvello, R, Cianciulli, A, Nicolardi, G, De Nuccio, F, Giannotti, L, Salvatore, R, Porro, Chiara, Trotta, Teresa, Panaro, Ma, Lofrumento, D.d. (2017). Vitamin D Treatment Attenuates Neuroinflammation and Dopaminergic Neurodegeneration in an Animal Model of Parkinson's Disease, Shifting M1 to M2 Microglia Responses.. JOURNAL OF NEUROIMMUNE PHARMACOLOGY, ISSN: 1557-1904, doi: 10.1007/s11481-016-9720-7 Q1.
- Cianciulli Antonia, Salvatore Rosaria, Porro Chiara, Trotta Teresa, Panaro Maria Antonietta (2016). Folic Acid Is Able to Polarize the Inflammatory Response in LPS Activated Microglia by Regulating Multiple Signaling Pathways. MEDIATORS OF INFLAMMATION, vol. 2016, ISSN: 1466-1861, doi: 10.1155/2016/5240127 Q2.
- Giovanna Elisiana, Trotta Teresa, Palladino Grazia Pia, Panaro Maria Antonietta, Zoppo Liugi Davide, Foschino Barbaro M.P., Porro Chiara (2016). Microparticles in sputum of COPD patients: A potential biomarker of the disease?. INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE, vol. 11, p. 527-533, ISSN: 1176-9106, doi: 10.2147/COPD.S99547 Q1 Last and correspondig author.
- Cianciulli Antonia*, Calvello Rosa*, Porro Chiara, Trotta Teresa, Salvatore Rosaria, Panaro Maria Antonietta (2016). PI3k/Akt signalling pathway plays a crucial role in the anti-inflammatory effects of curcumin in LPS-activated microglia. INTERNATIONAL IMMUNOPHARMACOLOGY, vol. 36, p. 282290, ISSN: 1567-5769, doi: 10.1016/j.intimp.2016.05.007.*These authors participated equally in this work Q2. Second author
- Posa Francesca, Di Benedetto Adriana, Colaianni Graziana, Cavalcanti- Adam Elisabetta A., Brunetti Giacomina, Porro Chiara, Trotta Teresa, Grano Maria, Mori Giorgio (2016). Vitamin D Effects on Osteoblasti Differentiation of Mesenchymal Stem Cells from Dental Tissues. STEM CELLS INTERNATIONAL, vol. 2016, ISSN: 1687-9678, doi: 10.1155/2016/9150819 Q2.
- Cianciulli A*, Dragone T*, Calvello R, Porro C, Trotta T, Lofrumento Dd, Panaro Ma. (2015). IL-10 plays a pivotal role in anti-inflammatory effects of resveratrol in activated microglia cells. INTERNATIONAL IMMUNOPHARMACOLOGY, vol. 24, p. 369-376, ISSN: 1567-5769, doi: 10.1016/j.intimp.2014.12.035. .*These authors participated equally in this work Q2.
- Porro Chiara*, Trotta Teresa*, Panaro Maria Antonietta (2015). Microvesicles in the brain: Biomarker, messenger or mediator?. JOURNAL OF NEUROIMMUNOLOGY, vol. 288, p. 70-78, ISSN: 0165-5728, doi: 10.1016/j.jneuroim.2015.09.006 .*These authors participated equally in this work. Q2 First and correspondig author.
- Porro Chiara*, Cianciulli Antonia*, Calvello Rosa, Panaro Maria Antonietta (2015). Reviewing the Role of Resveratrol as a Natural Modulator of Microglial Activities. CURRENT PHARMACEUTICAL DESIGN, vol. 21, p. 5277-5291, ISSN: 1873-4286, doi:http://www.eurekaselect.com/135273/article# .*These authors participated equally in this work Q2 First author.
- Trotta T*, Porro C*, Calvello R, Panaro MA. (2014). Biological role of Toll-like receptor-4 in the brain.. JOURNAL OF NEUROIMMUNOLOGY, vol. 268, p. 1-12, ISSN: 0165-5728, doi: 10.1016/j.jneuroim.2014.01.014 .*These authors participated equally in this work Q2 First author.
- Dragone T, Cianciulli A, Calvello R, Porro C, Trotta T, Panaro MA. (2014). Resveratrol counteracts lipopolysaccharide-mediated microglial inflammation by modulating a SOCS-1 dependent signaling pathway.. TOXICOLOGY IN VITRO, vol. Sep;28(6), p. 1126-1135, ISSN: 0887-2333, doi: 10.1016/j.tiv.2014.05.005 Q1.
- Trotta, Teresa, Guerra L., Piro D., D'Apolito, Maria, Piccoli, Claudia, Porro, Chiara, Giardino, Ida, Lepore S., Castellani, Stefano, Di Gioia, Sante, Petrella A., Maffione, Angela Bruna, Casavola V., Capitanio, Nazzareno, Conese, Massimo (2014). Stimulation of beta2-adrenergic receptor increases CFTR function and decreases ATP levels in murine hematopoietic stem/progenitor cells. JOURNAL OF CYSTIC FIBROSIS, vol. 14, p. 26-33, ISSN: 1569-1993, doi: 10.1016/j.jcf.2014.08.005 Q1.
- Lepore S., Milillo L., Trotta T., Castellani S., Porro C., Panaro M.A., Santarelli A., Bambini F., Lo Muzio L., Conese M., Maffione A.B. (2013). Adhesion and growth of osteoblast-like cells on laserengineered porous titanium surface: expression and localization of N-cadherin and beta-catenin. JOURNAL OF BIOLOGICAL REGULATORS & HOMEOSTATIC AGENTS, vol. 27, p. 531-541, ISSN: 0393-974X Q3.
- Soleti R, Porro C, Martínez MC. (2013). Apoptotic process in cystic fibrosis cells.. APOPTOSIS, vol. Set;18, p. 1029-1038, ISSN: 1360-8185, doi: 10.1007/s10495-013-0874-y. Q1. Second author
- T. Trotta, S. Di Gioia, D. Piro, S. Lepore, S. Cantatore, C. Porro, S. Castellani, A. Petrella, F. Fortunato, A. B. Maffione, M. Conese (2013). Effect of acute lung injury on VLA-4 and CXCR4 expression in resident and circulating hematopoietic stem/progenitor cells. RESPIRATION, vol. 85, p. 252-264, ISSN: 0025-7931, doi: 10.1159/000341172 Q1.
- Porro, Chiara, Di Gioia, Sante, Trotta, Teresa, Lepore Silvia., Panaro Maria. Antonietta., Battaglino A., Ratclif Luigi., Castellani, Stefano, Bufo, Pantaleo, Martinez Maria. Carmen., Conese, Massimo (2013). Pro-inflammatory effect of cystic fibrosis sputum microparticles in the murine lung. JOURNAL OF CYSTIC FIBROSIS, vol. 12, p. 721-728, ISSN: 1569-1993, doi: 10.1016/j.jcf.2013.03.002 Q1 First author.
- PORRO C., LEPORE S., TROTTA T., CASTELLANI S., RATCLIF L., BATTAGLINO A., DI GIOIA S., MARTÍNEZ M.C., CONESE M., MAFFIONE A. (2010). Isolation and characterization of microparticles in sputum from cystic fibrosis patients. RESPIRATORY RESEARCH, vol. 11(1), p. 94-104, ISSN: 1465-9921 Q1 First and correspondig author.
- BENAMEUR T*, SOLETI R*, C. PORRO, ANDRIANTSITOHAINA R, MARTÍNEZ MC (2010). Microparticles carrying Sonic hedgehog favor neovascularization through the activation of nitric oxide pathway in mice.. PLOS ONE, ISSN: 1932-6203 .*These authors participated equally in this work Q1. Second author
- PRICCI M*, BOURGET JM*, ROBITAILLE H, C. PORRO, SOLETI R, MOSTEFAI HA, AUGER FA, MARTINEZ, MC, ANDRIANTSITOHAINA R, GERMAIN L (2009). Applications of human tissueengineered blood vessel models to study the effects of shed membrane microparticles from Tlymphocytes on vascular function.. TISSUE ENGINEERING, PART A, vol. 15 (1), p. 137-145, ISSN: 1937-3341 *These authors participated equally in this work Q1 .
- SOLETI R*, BENAMEUR T*, C. PORRO, PANARO MA, ANDRIANTSITOHAINA R, MARTÍNEZ MC (2009). Microparticles harboring Sonic Hedgehog promote angiogenesis through the up-regulation of adhesion proteins and pro-angiogenic factors.. CARCINOGENESIS, vol. 30 (4), p. 580-588, ISSN: 0143-3334 .*These authors participated equally in this work Q1. Second author
- C. PORRO, SOLETI R, BENAMEUR T, MAFFIONE AB, ANDRIANTSITOHAINA R AND MARTINEZ MC (2009). Sonic Hedgehog Pathway as a Target for Therapy in Angiogenesis-Related Diseases. CURRENT SIGNAL TRANSDUCTION THERAPY, vol. 4, p. 31-45, ISSN: 1574-3624 Q4 First author.
- PANARO MA, MITOLO CI, ACQUAFREDDA A, CIANCIULLI A, LISI S, C. PORRO, MITOLO V (2008). Mutation patterns in the chemokine CXC receptor 4 gene subfamily.. IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY, vol. 30, p. 475-488, ISSN: 0892-3973 Q2.
- PANARO MA, MITOLO CI, ACQUAFREDDA A, CIANCIULLI A, C. PORRO, MITOLO V (2008). Mutation, selection, and functional repair in formyl peptide receptor genes: a view on the selection processes occurring in this gene subfamily.. IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY, vol. 30, p. 383-397, ISSN: 0892-3973 Q2.
- AGOUNI A*, MOSTEFAI HA*, PORRO C, CARUSIO N, FAVRE J, RICHARD V, HENRION D, MARTÍNEZ MC, ANDRIANTSITOHAINA R. (2007). Sonic hedgehog carried by microparticles corrects endothelial injury through nitric oxide release. FASEB JOURNAL, vol. 21(11); p. 2735-2741, ISSN: 0892-6638*These authors participated equally in this work Q1 Second author.
- DERVAUX T*, PORRO C*, KUNZELMANN C, FREYSSINET JM, MARTÍNEZ MC. (2006). Cyclic GMP modulates store-operated calcium entry inducing phosphatidylserine translocation at the surface of megakaryocytic cells. BIOCHIMIE, vol. 88(9); p. 1175-1182, ISSN: 0300-9084*These authors participated equally in this work. Q1 First author.
- DE SALVATORE G, DE SALVIA MA, PIEPOLI AL, NATALE L, PORRO C, NACCI C, MITOLO CI, MITOLO-CHIEPPA D. (2003). Effects of in vivo treatment with interleukins 1beta and 6 on rat mesenteric vascular bed reactivity. AUTONOMIC & AUTACOID PHARMACOLOGY, vol. 2; p. 125-131, ISSN: 1474-8665
- TROTTA, TERESA, POSA, FRANCESCA, MORI, GIORGIO, PORRO, CHIARA (2017). Dairy Products and Their Role in Human Health. In: Teresa Trotta Francesca Posa Giorgio Mori Chiara Porro. Dairy Products and Their Role in Human Health. p. 248-261, ISBN: 9781118906460, doi: 10.1002/9781118906460.ch2f Last author. (Chapter in Book)
AWARDS:
- 2003-2004: Erasmus scholarship for a stage at University Louis Pasteur Strasbourg.
- 2005-2007: Postdoc fellowship at University of Bari.
- 2006: Research Award from Italian Society of Pharmacology (SIF).
- 2010: Research Award from Foggia University “Premio Montel”.
